Meditation 8.41
41. An obstacle to sense perception is injurious to animal nature; an obstacle to impulse is equally injurious to animal nature. (And something else may similarly be an obstacle and injurious to the constitution of a plant). Thus then an obstacle to reason is injurious to a reasoning nature. Transfer, therefore, all these considerations to yourself. Perhaps pain and pleasure are affecting you. Sense affection must look to it. Did an obstacle oppose your impulse? If you started out to satisfy it without mental reservation, the obstacle is at once injurious to you as a reasonable being; but if you experience the general lot, you are not yet hurt or hindered. The properties of the mind, you know, no one else is wont to hinder, for neither fire nor steel nor despot nor abuse affect it one whit, when it has become 'a sphere rounded and at rest'.